In a world where marketing messages are ubiquitous and consumers try to shield themselves from message proliferation by subscribing to do not call lists and using spam blockers, what hope do researchers have to meet the high sampling standards upon which data reliability is predicated? Furthermore, as Internet and E-panels enable busy research departments to meet their company?s ever increasing demand for international research faster and cheaper, consumers are increasingly polled for their opinions. This paper presents an approach to understand ?what works? in terms of consumer responses to e-mail invitations to participate in internet-based surveys.