Previous literature has shown the effects of question wording or visual design on the data provided by respondents. However, few articles have been published that link the effects of question wording and visual design to the development of questionnaire design guidelines. This article proposes specific guidelines for the design of establishment surveys within statistical agencies based on theories regarding communication and visual perception, experimental research on question wording and visual design, and findings from cognitive interviews with establishment survey respondents. The guidelines are applicable to both paper and electronic instruments, and cover such topics as the phrasing of questions, the use of space, the placement and wording of instructions, the design of answer spaces, and matrices.